Available on request
EDTA
EDTA (ethylenediaminetetraacetic acid) salts are used to anticoagulate whole blood for haematological investigations, as the cellular components of the blood are particularly well preserved by EDTA. The anticoagulation is achieved by the EDTA forming complexes with metal ions such as calcium, therefore inhibiting the coagulation cascade. Anticoagulation with EDTA is irreversible. The EDTA concentration in BD Vacutainer® Tubes is 1.8 mg/mL of whole blood, as recommended by the International Council Society of Haematology (ICSH).The ICSH recommends dipotassium EDTA salt (K2EDTA) for haematological investigations.
To avoid micro-clotting, mix the EDTA tube with 8-10 inversions immediately after the blood sample has been taken.
Plastic tube with K2 EDTA and a BD Hemogard closure.