In healthy horses, SAA is virtually undetectable, but in acute inflammation it increases within 6-12 hours and peaks at 1000-fold the baseline value. This is a faster and greater increase than, for example, fibrinogen.

As the inflammatory response subsides, it begins to decline within 12-24 hours. The dynamic nature of SAA makes it an ideal marker to evaluate disease severity and to monitor disease progression or improvement. SAA is well suited to evaluate response to treatment.

More information about SAA tests:
https://www.grovet.com/nl_be/catalog/product/view/id/2536/s/vmrd-saa-reader-plus-45-saa-tests-lfd-saastart/category/2/