Pro-Stride APS - Protein Solution 6 Pack

Pro-Stride APS

Pro-Stride APS (autologous protein solution) is a dual-device which offers an all-natural option for horses experiencing joint lameness. The output, ready to use within 30 minutes, consists of a concentrated solution of white blood cells, platelets, growth factors and anti-inflammatory cytokines (including IL-1ra among others).

Please note: you will need a Veterinary Centrifuge and ACD-A to use this product.

The advantages of the use of Pro-Stride can be summarized as follows:

• All-Natural
• Clinically demonstrated effectiveness
• Inflammation and pain relief up to 52 weeks (long term effect)*
• < 30 minute treatment 
• Ambulatory convenience
• No freezing required (No denaturalization)
• No incubation required (No increase in pro-inflammatory factors, ↓ risk of contamination)
• Better cellular and cytokine profile for blocking inflammation compared to similar devices

* A. Bertone, Am J Vet Res 2014; 75:141-151

There are several naturally occurring inhibitors (anti-inflammatory proteins) of the pro-inflammatory cytokines IL-1 and TNF-alpha. These include the interleukin-1 receptor antagonist protein (IRAP), also known as IL-1ra, SIL-1r, also known as Soluble interleukin-1 receptor and STNF-rs, known as Soluble tumour necrosis factor receptors. All of these are highly concentrated within Pro-Stride APS.

The output of the Pro-Stride system consists of a concentrated solution of white blood cells, platelets, growth factors (IGFI, HGF, TGF-β, PDGF, FGF2, VEGF, EGF) and anti-inflammatory cytokines (IRAP/IL1ra, sIL1R, sTNFRI and II, IL-10). This combination of molecules not only neutralizes IL-1β and TNF-α, key cytokines for chronic inflammation, but also aid in the healing process of damaged tissues.  

The Pro-Stride APS system consists of two different devices:

• Separator device: The first device produces an enriched PRP or ePRP (Platelet Rich Plasma + buffy coat). This PRP can be used directly for soft tissue injuries such as tendons, ligaments or wounds. It is commercially available under the name of Restigen.
• APS Concentrator device: The ePRP is to be loaded into the second device which contains desiccant polyacrylamides crystal beads. These crystals absorb the residual moisture from the PRP increasing the final concentrations.